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백광현 (Kwang-Hyun Baek, Ph.D.)  
[Personal]

Professor,
Department of Biomedical Science
CHA University, CHA General Hospital
335 Pangyo-Ro, Bundang-Gu,
Seongnam-Si, Gyeonggi-Do 13488, Republic of Korea
    
Tel: 82-31-881-7223
Fax: 82-31-881-7249
Email: baek@cha.ac.kr

[Education & Career]

Ph.D. Iowa State University, Ames, Iowa, USA (1990~1995)
Post-Doc. Harvard Medical School (Howard Hughes Medical Institute / Brigham and Women's Hospital / Dana-Farber Cancer Institute), Boston, Massachusettes, USA (1996~1999)
Assistant Professor, CHA University (1999~2002)
Associate Professor, CHA University (2002~2007)
Chairman, Graduate School of Life Science and Biotechnology, CHA University (2002~2007)
Vice-Director, Cell and Gene Therapy Research Institute, CHA University (2003~2014)
Vice-Director, CHA Stem Cell Institute, CHA University (2006~2014)
Professor, Department of Biomedical Science, CHA University (2007~present)
Visiting Professor. Harvard Medical School (Dana-Farber Cancer Institute), Boston, Massachusettes, USA (2012~2013)
Dean, College of Life Sciences, CHA University (2014~2016)
Director, Cell and Gene Therapy Research Institute, CHA Univeristy (2014~present)
Professor, Graduate School of Life Sciences, CHA University (2017~present)
Editor-in-Chief, International Journal of Immunotherapy and Cancer Research (2017~present)

[Publications] * Corresponding author (책임/주관 저자)

[2019 : SCI]

  • * 148. Park, J.-H., Kim, S.-Y., Cho, H.-J., Lee, S.-Y., and Baek, K.-H. (2019). YOD1 deubiquitinates NEDD4 involved in the Hippo signaling pathway. Cell. Physiol. Biochem. in press (Corresponding author)

  • * 147. Woo, B., and Baek, K.-H. (2019). Interplay of deubiquitinating enzymes and cytokines. Cytokine & Growth Factor Rev. 48: 40-51. (Corresponding author)

  • * 146. Lee, H.-R., and Baek, K.-H. (2019). The role of natural killer cells for immunotherapy in chronic myeloid leukemia (CML). Oncol. Rep. 41(5): 2625-2635. (Corresponding author)

  • * 145. Kim, S.-Y., and Baek, K.-H. (2019). TGF-beta signaling pathway mediated by deubiquitinating enzymes. Cell. Mol. Life Sci. 76(4): 653-665. (Corresponding author)

  • * 144. Lee, D.-H., Pei, C.-Z., Song, J.-Y., Lee, K.-J., Yun, B.-S., Kwack, K.-B., Lee, E.-I., and Baek, K.-H. (2019). Identification of serum biomarkers for premature ovarian failure. BBA - Proteins and Proteomics, 1867(3): 219-226. (Corresponding author)


[2019 : non-SCI]

  • * 143. Pei, C.-Z, Kim, Y. J., and Baek, K.-H. (2019). Pathogenetic factors involved in recurrent pregnancy loss from multiple aspects. Obstetrics & Gynecology Science, 62(4): 212-223. (Corresponding author)


[2018 : SCI]

  • * 142. Li, L., Choi, B.-C., Ryoo, J.E., Song, S.-J., Pei, C.-Z.,  Lee, K.Y., Paek, J., and Baek, K.-H. (2018). Opposing roles of inter--trypsin inhibitor heavy chain 4 in recurrent pregnancy loss. EBioMedicine, 37: 535-546.(Corresponding author)

  • 141. Kim, K.E., Heo, J. S., Han, S., Kwon, S.-K., Kim, S.-Y., Kim, J.H., Baek, K.-H., and Sheen, Y. H. (2018). Blood concentrations of lipopolysaccharide-binding protein, high-sensitivity C-reactive protein, tumor necrosis factor-α, and Interleukin-6 in relation to insulin resistance in young adolescents. Clin. Chim. Acta 486: 115-121.

  • * 140. Kim, S.-Y., Choi, J., Lee, D.-H., Park, J.-H., Hwang, Y.-J., and Baek, K.-H. (2018). PME-1 is regulated by USP36 in ERK and Akt signaling pathways. FEBS Lett. 592(9): 1575-1588. (Corresponding author)

  • * 139. Choi, J., and Baek, K.-H. (2018). Cellular functions of stem cell factors mediated by the ubiquitin-proteasome system. Cell. Mol. Life Sci. 75: 1947-1957. (Corresponding author)

  • 138. Kim, J.H., Heo, J.S., Baek, K.S., Kim, S.-Y., Kim, J.H., Baek, K.-H., Kim, K.E., and Sheen, Y.H. (2018). Zonulin level, a marker of intestinal permeability, is increased in association with liver enzymes in young adolescents. Clin. Chim. Acta 481: 218-224.

  • * 137. Kim, S.-Y., Kwon, S.-K., Lee, S.-Y., and Baek, K.-H. (2018). Ubiquitin-specific peptidase 5 and ovarian tumor deubiquitinase 6A are differentially expressed in p53+/+ and p53-/- HCT116 cells. Int. J. Oncol. 552: 1705-1714. (Corresponding author)


[2018 : non-SCI]

  • * 136. Kang, S.-J. Kim, S.-H., and Baek, K.-H. (2018). Effects of short-term clinical art therapy in firefighters with post-traumatic stress risk. Journal of Complementary Medicine & Alternative Healthcare, 8(4): JCMAH.MS.ID.555742. (Corresponding author)

  • * 135. Baek, K.-H. (2018). Regulation of protein degradation and homeostasis by the cytokine-inducible deubiquitinating enzymes. Int. J. Immunother Cancer Res. 4: 1-3. (Corresponding author)


[2017 : SCI]

  • * 134. Kwon, S.-K., Saindane, M., and Baek, K.-H. (2017). p53 stability is regulated by diverse deubiquitinating enzymes. BBA - Rev. on Cancer, 1868: 404-411. (Corresponding author)

  • 133. Kim, Y.-J., Hur, J., Cho, E.-H., Baek, K.-H., and Lee, K.-J. (2017). Prediction of gestational diabetes mellitus by unconjugated estriol levels in maternal serum. Int. J. Med. Sci. 14(2): 123-127.

  • * 132. Kwon, S.-K., Kim, E.-H., and Baek, K.-H. (2017). RNPS1 is modulated by ubiquitin-specific protease 4. FEBS Lett. 591(2): 369-381. (Corresponding author)

  • * 131. Kwon, S.-K., Lee, D.-H., Kim, S.-Y., Park, J.-H., Choi, J.-H., and Baek, K.-H. (2017). Ubiquitin-specific protease 21 regulating the K48-linked polyubiquitination of NANOG. Biochem. Biophys. Res. Commun. 482: 1443-1448. (Corresponding author)


[2016 : SCI]

  • * Li, L., and Baek, K.-H.. (2016). Genetics of Polycystic Ovary Syndrome: How Far Have We Come? In "Polycystic Ovary Syndrome (PCOS): Clinical Aspects, Potential Complications and Dietary Management". Nova Science Publishers, (ISBN: 978-1-63485-955-4)

  • * 130. Park, J.-H., Li, L., Choi, J.-W., and Baek, K.-H. (2016). The association of-429T>C and -374T>A polymorphisms in the RAGE gene with polycystic ovary syndrome. Int. J. Med. Sci. 13(6): 451-456. (Corresponding author)

  • * 129. Lim, K.-H., Choi, J.-H., Park, J.-H., Cho, H.-J., Park, J.-J., Lee, E.-J., Li, L., Choi, Y.-K., and Baek, K.-H. (2016). Ubiquitin specific protease 19 involved in transcriptional repression of retinoic acid receptor by stabilizing CORO2A. Oncotarget, 7(23): 34759-34772. (Corresponding author)

  • 128. Chung, S., Rho, S., Kim, G., Kim, S.-R., Baek, K.-H., Kang, M., and Lew, H. (2016). Human cord blood cells and chorionic plate-derived mesenchymal stem cells promote axon survival in an optic nerve crush rat model. Int. J. Mol. Med. 37(5): 1170-1180.

  • * 127. Lim, K.-H., Suresh, B., Park, J.-H., Kim, Y.-S., Ramakrishna, S., and Baek, K.-H. (2016). Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth. Oncotarget, 7(22): 14441-14457. (Corresponding author)

  • * 126. Baek, K.-H. (2016). Meet Our Editorial Board Member. Curr. Protein & Pept. Sci. 17(4): 1. (Corresponding author)

  • * 125. Lim, K.-H., Song, M.-H., and Baek, K.-H. (2016). Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint. Cell. Mol. Life Sci. 73(7): 1439-1455. (Corresponding author)


[2016 : non-SCI]

  • 124. Kim, K. E., Cho, Y. S., Baek, K. S., Li, L., Baek, K.-H., Kim, J. H., Kim, H.-S., Sheen, Y. H. (2016). Lipopolysaccharide-binding protein plasma levels as a biomarker of obesity-related insulin resistance in adolescents. Kor. J. Pediatr. 59(5): 231-238.


[2015 : SCI]

  • 123. Ahn, H.-J., Kim, K.-S., Shin, K.-W., Lim, K.-H., Kim, J.-O., Lee, J.-Y., Kim, J., Park, J.-H., Yang, K.-M., Baek, K.-H., Ko, J.-J., and Park, K.-S. (2015). Ell3 induces p53 stabilization following CDDP treatment by modulating ubiquitin-dependent and -independent proteasomal degradation pathways in the breast cancer cells. Oncotarget, 6(42): 44523-44537.

  • * 122. Kim, J.-O,, Kim, S.-R., Lim, K.-H., Kim, J.-H., Ajjappala, B., Lee, H.-J., Choi, J.-I., and Baek, K.-H. (2015). Deubiquitinating enzyme USP37 regulating oncogenic function of 14-3-3γ. Oncotarget, 6(34): 36551-36576. (Corresponding author)

  • * 121. Lim, K.-H., Park, J.-J., Gu, B.-H., Kim, J.-O, Park, S.-G., and Baek, K.-H. (2015). HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response. Sci. Rep. 5: 12793. (Corresponding author)

  • * 120. Park, J.-H., Li, L., and Baek, K.-H. (2015). Association of T869C polymorphism of transforming growth factor-β1 gene with polycystic ovary syndrome. Mol. Med. Rep. 12(3): 4560-4565. (Corresponding author)

  • * 119. Li, L., and Baek, K.-H. (2015). Molecular genetics of polycystic ovary syndrome: an update. Curr. Mol. Med. 15(4): 331-342. (Corresponding author)

  • * 118. Li, L., Ryoo, J.-E., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2015). Genetic variation in the Mcp-1 gene promoter associated with the risk of polycystic ovary syndrome. PLoS One. 10(4): e0123045. (Corresponding author)

  • * 117. Li, L., Yun, J.-H., Yoo, J.-E., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2015). 54G/C polymorphism of SREBF-1 gene is associated with polycystic ovary syndrome. Eur. J. Obs. Gyn. Reprod. Biol. 188: 95–99. (Corresponding author)

  • * 116. Kim, S.-R., Kim, J.-O., Lim, K.-H., Yun, J.-H., Han, I., and Baek, K.-H. (2015). Regulation of pyruvate kinase isozyme M2 is mediated by the ubiquitin-specific protease 20. Int. J. Oncol. 46: 2116-2124. (Corresponding author)

  • * 115. Park, J.-J., Lim, K.-H., and Baek, K.-H. (2015). Annexin-1 regulated by HAUSP is essential for UV-induced damage response. Cell Death & Dis. 6:e1654. (Corresponding author)

  • * 114. Ramakrishna, S., Suresh, B., and Baek, K.-H. (2015). Biological functions of hyaluronan and cytokine-inducible deubiquitinating enzymes. BBA - Rev. on Cancer, 1855 (1): 83-91. (Corresponding author)


[2015 : non-SCI]

  • 113. Schvartz, D., Bergsten, P., Baek, K.-H.. Barba De La Rosa, A., Cantley, J., Dayon, L., Finamore, F., Fontana, P., Gaudet, P., Goo, Y.A., Moulder, R., Goodlett, D., Johnson, J.D., Konvalinka, A., Mulde,r H., Priego-Capote, F., Sechi, S., Snyder, M., Tiss, A., Wiederkehr, A., Xenarios, I., Kussmann, M., and Sanchez, J.-C. (2015). The human diabetes proteome project (HDPP): The 2014 update. Translational Proteomics. 8-9: 1-7


[2014 : SCI]

  • * Baek, K.-H., Lim, K.-H. and Park, J.-J. (2014). Deubiquitinating enzymes as novel targets for cancer therapies. In "Resistance to proteasome inhibitors in cancer". Springer, (eISBN: 978-3-319-06752-0, ISBN: 978-3-319-06751-3)

  • * 112. Ramakrishna, S., Kim, K.-S., and Baek, K.-H. (2014). Posttranslational modifications of defined embryonic reprogramming transcription factors. Cell Reprogram. 16 (2): 108-120. (Corresponding author)

  • * 111. Lim, K.-H., Kim, S.-R., Ramakrishna, S., and Baek, K.-H. (2014). Critical lysine residues of Klf4 required for protein stabilization and degradation. Biochem. Biophys. Res. Commun. 443: 1206-1210. (Corresponding author)


[2013 : SCI]

  • * Baek, K.-H. (2013). Cytokine-regulated protein degradation by the ubiquitination system. In "Advances in Protein and Peptide Sciences". Bentham Science Publishers, Vol 1, pp 256-271. (eISBN: 978-1-60805-487-9, ISBN: 978-1-60805-631-6, ISSN :2213-9869)

  • 110. Lee, K.W., Cho, J.G., Kim, C.M. Kang, A.Y., Kim, M., Ahn, B.Y., Chung, S.S., Lim, K.-H., Baek, K.-H., Sung, J.-H., Park, K.S., and Park, S.G. (2013). Herpesvirus-Associated Ubiquitin-Specific Protease (HAUSP) modulates peroxisome proliferator-activated receptor gamma (PPARr) stability through its deubiquitinating activity. J Biol Chem, 288 (46): 32886-32896.

  • * 109. Lim, K.-H., Ramakrishna, S., and Baek, K.-H. (2013). Molecular mechanisms and functions of cytokine-inducible deubiquitinating enzymes. Cyt. Growth Factor Rev. 24 (5): 427-431. (Corresponding author)

  • * 108. Li, L., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2013). Relationship between leptin receptor and polycystic ovary syndrome. Gene, 527 (1): 71-74. (Corresponding author)

  • * 107. Park, J.-J., Yun, J.-H., and Baek, K.-H. (2013). Polyclonal and monoclonal antibodies for ubiquitin specific protease 20. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. Monoclon Antib Immunodiagn Immunother. 32 (3):193-199. (Corresponding author)

  • * 106.  Lim, K.-H., and Baek, K.-H. (2013). Ubiquitin-specific proteases as therapeutic targets in cancer . Curr. Pharm. Des. 19 (22): 4039-4052. (Corresponding author)

  • * 105. Kim, Y.-S., Gu, B.-H. Choi, B.-C. Kim, M.-S., Song, S., Yun, J.-H., Chung, M.-K., Choi, C.-H., and Baek, K.-H. (2013). Apolipoprotein A-IV as a novel gene associated with polycystic ovary syndrome. Int. J. Mol. Med. 31 (3): 707-716. (Corresponding author)

  • * 104.  Choi, J.-H., Lim, K.-H., Park, E., Kim, J.-Y., Choi, Y.-K., and Baek, K.-H. (2013). Glutamate-ammonia ligase and reduction of G0 population in PANC-1 cells. J. Cell. Biochem. 114 (2): 303-313. (Corresponding author)


[2012 : SCI]

  • * 103. Baek, K.-H., Lee, H., Yang, S., Lim, S.-B., Lee, W., Lee, J.E., Lim, J.-J., Jun, K., Lee, D.-R., and Chung, Y. (2012). Embryonic demise caused by targeted disruption of a cysteine protease Dub-2. PLoS One, 7: e44223. (Corresponding author)

  • * 102. Yun, J.-H., Gu, B.-H., Kang, Y.-B., Choi, B.-C., Song, S., and Baek, K.-H. (2012). Association between INS-VNTR polymorphism and polycystic ovary syndrome in a Korean population. Gynecol. Endocrinol, 28 (7): 525-528. (Corresponding author)

  • * 101. Ramakrishna, S., Suresh, B., Bae, S.-M., Ahn, W.-S., Lim, K.-H., and Baek, K.-H. (2012). Hyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity. PLoS One, 7: e37772. (Corresponding author)

  • * 100. Suresh, B., Ramakrishna, S., and Baek, K.-H. (2012). Diverse roles of a scaffolding protein RanBPM. Drug Discov. Today, 17: 379-387. (Corresponding author)


[2012 : non-SCI]

    * 99. Baek,  K.-H., and Suresh, B. (2012). RANBP9 (RAN binding protein 9). Atlas Genet Cytogenet Oncol Haematol. 16 (8): 549-551. (Corresponding author)

[2011 : SCI]

  • * 98. Yun, J.-H., Choi, J.-W., Lee, K.-J.,Shin, J.-S., and Baek, K.-H. (2011). The promoter -1031(T/C) polymorphism in tumor necrosis factor-alpha associated with polycystic ovary syndrome. Reprod. Biol. Endocrinol. 9: 131. (Corresponding author)

  • * 97. Choi, J.-H., Lee, M.-Y., Ramakrishna, S., Kim, Y., Shim, J.-Y. Han, S.-M., Kim, J.-Y., Lee, D.-H., Choi, Y.-K., and Baek, K.-H. (2011). LCP1 up-regulated by partial pancreatectomy supports cell proliferation and differentiation. Mol. BioSyst. 7 (11): 3104-3111. (Corresponding author)

  • * 96. Kim, J.-H., Li, L., Yun, J.-H., Choi, B.-C., and Baek, K.-H. (2011). Association study between the -866G/A polymorphism in the promoter of uncoupling protein-2 gene and polycystic ovary syndrome. Mol. Med. Rep. 4: 747-751. (Corresponding author)

  • 95. Bang, J.-Y., Kim, E.-Y., Kang, D.-K., Chang, S.-I., Han, M.-H., Baek, K.-H. and Kang, I.-C. (2011). Pharmaco-proteomic analysis of a novel cell-permeable peptide inhibitor of tumor-induced angiogenesis. Mol. Cell. Proteomics, 10: M110.005264

  • * 94. Ramakrishna, S., Suresh, B., Lim, K.-H., Cha, B.-H., Lee, S.-H., Kim, K.-S., and Baek, K.-H. (2011). PEST motif sequence regulating human NANOG for proteasomal degradation. Stem Cells Dev. 20 (9): 1511-1519. (Corresponding author)

  • * 93. Kim, M.-S., Gu, B.-H., Song, S., Choi, B.-C., Cha, D.-H., and Baek, K.-H. (2011). ITI-H4, as a biomarker in the serum of recurrent pregnancy loss patients. Mol. BioSyst. 7: 1430-1440. (Corresponding author)

  • * 92. Ramakrishna, S., Suresh, B., Lee, E.-J., Lee, H.-J., Ahn, W.-S., and Baek, K.-H. (2011). Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. J. Biol. Chem. 286: 10505-10514. (Corresponding author)

  • * 91. Kim, M.-S., Ramakrishna, S., Lim, K.-H., Kim, J.-H., and Baek, K.-H. (2011). Protein stability of mitochondrial superoxide dismutase SOD2 is regulated by USP36. J. Cell. Biochem. 112: 498-508. (Corresponding author)

  • * 90. Lan, L., Yun, J.-H., Lee, J.-H., Song, S., Choi, B.-C., and Baek, K.-H. (2011). Association study of +45G15G (T/G) and +276 (G/T) polymorphisms in the adiponectin gene with polycystic ovary syndrome. Int. J. Mol. Med. 27: 283-287. (Corresponding author)

  • * 89. Ramakrishna, S., Suresh, B., and Baek, K.-H. (2011).The role of deubiquitinating enzymes in apoptosis. Cell. Mol. Life Sci. 68: 15-26. (Corresponding author)


[2010 : SCI]

  • * 88. Suresh, B., Ramakrishna, S., Kim, Y.-S., Kim, S.-M., Kim, M.-S., and Baek, K.-H. (2010). Stability and function of mammalian lethal giant larvae-1 oncoprotein are regulated by the scaffolding protein RanBPM. J. Biol. Chem. 285: 35340-35349. (Corresponding author)

  • * 87. Suresh, B., Ramakrishna, S., Lee, H.-J., Choi, J.-H., Kim, J.-Y., Ahn, W.-S., and Baek, K.-H. (2010). K48- and K63-linked polyubiquitination of deubiquitinating enzyme USP44. Cell Biol. Int. 34: 799-808. (Corresponding author)

  • * 86. Gu, B.-H., Park, J.-M., and Baek, K.-H. (2010). Genetic variations of FSHR are associated with polycystic ovary syndrome. Int. J. Mol. Med. 26: 107-112. (Corresponding author)

  • * 85. Choi, J.-H., Lee, M.-Y., Kim, Y., Shim, J.-Y., Han, S.-M., Lee, K.-A., Choi, Y.-K., Jeon, H.-M., and Baek, K.-H. (2010). Isolation of genes involved in pancreas regeneration by subtractive hybridization. Biol. Chem. 391: 1019-1029. (Corresponding author)

  • * 84. Ramakrishna, S., Suresh, B., Kang, I.-C., and Baek, K.-H. (2010). Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme. Hybridoma, 29: 311-319. (Corresponding author)

  • 83. Noh, S.M., Park, M.O., Shim, G., Han, S.E., Lee, H.Y., Huh, J.H., Kim, M.S., Bang, S.S., Kim, K., Kwon, I.C., Kim, J.-S., Baek, K.-H., and Oh, Y.-K. (2010). Pegylated poly-L-arginine derivatives of chitosan for effective delivery of siRNA. J. Control. Release, 145: 159-164.


[2009 : SCI]

  • * 82. Gu, B.-H., and Baek, K.-H. (2009). Follicular-stimulating hormone receptor (FSHR) polymorphisms and polycystic ovary syndrome (PCOS). Fertil. Steril. 92: e55 (Corresponding author)

  • 81. Jo, A.-Y., Kim, M.-Y., Lee, H.-S., Rhee, Y.-H., Lee, J.-E., Baek, K.-H., Park, C.-H., Koh, H.-C., Shin, I., Lee, Y.-S., and Lee, S.-H. (2009). Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant Nurr1 mutant. Stem Cells 27: 2238-2246.

  • * 80. Ajjappala, B., Kim, M.-S., Kim, E.-Y., Kim, J.-H., Kang, I.-C., and Baek, K.-H. (2009). Protein chip analysis of pluripotency associated proteins in NIH3T3 fibroblast. Proteomics 9: 3968-3978. (Corresponding author)

  • * 79. Choi, S.-W., Gu, B.-H., Ramakrishna, S., Park, J.-M., and Baek, K.-H. (2009). Association between a single nuclotide polymorphism in MTHFR gene and polycystic ovary syndrome. Eur. J. Obs. Gyn. Reprod. Biol. 145: 85-88.(Corresponding author)

  • 78. Ait-Ali, T., Wilson, A.W., Finlayson, H., Carre, W., Ramaiahgari, S.C., Westcott, D.G., Waterfall, M., Frossard, J.P., Baek, K.-H., Drew, T.W., Bishop, S.C., and Archibald, A.L. (2009). Functional analysis of the porcine USP18 and its role during porcine arterivirus replication. Gene 439: 35-42.

  • * 77. Gu, B.-H., and Baek, K.-H. (2009). Pro12Ala and His447His polymorphisms of PPAR-gamma are associated with polycystic ovary syndrome. Reprod. BioMed. Online 18: 644-650. (Corresponding author)

  • * 76. Ajjappala, B.S., Kim, Y.-S., Kim, M.-S., Lee, M.-Y., Lee, K.Y., Ki, H.-Y., Cha, D.-H., and Baek, K.-H. (2009). 14-3-3gamma is stimulated by IL-3 and promotes cell proliferation. J. Immunol. 182: 1050-1060. (Corresponding author)


[2009 : non-SCI]

  • * 75. Baek, K.-H. and Ramakrishna, S. (2009). USP7 (ubiquitin specific peptidase 7 (herpes virus-associated)). Atlas Genet Cytogenet Oncol Haematol. 2009; 13 (8): 576-579. (Corresponding author)


[2008 : SCI]

  • * 74. Lee, M.-Y., Ajjappala, B.S., Kim, M.-S., Oh, Y.-K., and Baek, K.-H. (2008). DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway. J. Cell. Biochem. 105: 1420-1429. (Corresponding author)

  • * 73. Park, J.-M., Lee, E.-J., Ramakrishna, S., Cha, D.-H., and Baek, K.-H. (2008). Association study for single nucleotide polymorphisms in the CYP17A1 gene and polycystic ovary syndrome. Int. J. Mol. Med. 22: 249-254. (Corresponding author)

  • * 72. Lee, E.-J., Oh, B., Lee, J.-Y., Kimm, K., Park, J.-M., and Baek, K.-H. (2008). Association study between single nucleotide polymorphisms in the VEGF gene and polycystic ovary syndrome (PCOS). Fertil. Steril. 89: 1751-1759. (Corresponding author)

  • * 71. Lee, E.-J., Oh, B., Lee, J.-Y., Kimm, K., Lee, S.-H., and Baek, K.-H. (2008). A single nucleotide polymorphism of INSR gene for polycystic ovary syndrome. Fertil. Steril. 89: 1213-1220. (Corresponding author)

  • 70.  Jin, Y.-H., Kim, Y.-J., Kim, D.-W., Baek, K.-H., Kang, B. Y., Yeo, C.-Y., and Lee, K.-Y. (2008). Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53. Biochem. Biophys. Res. Commun. 368: 690-695.

  • * 69. Park, J.-M., Gu, B.-H., Lee, E.-J., Kim, J.-Y., Choi, S.-W., and Baek, K.-H. (2008). A single nucleotide polymorphism in exon 7 of sorbin and SH3-domain-containing-1 (SORBS1) in Korean PCOS patients. Mol. Med. Rep. 1: 93-97.


[2008 : non-SCI]

  • * 68. Kim, D.C., Noh, S.M., Kim, Y.B., Baek, K.-H., and Oh, Y.-K. (2008). Transdermal delivery of ceramide using sodium deoxycholate-based deformable liposomes. J. Kor. Pharm. Sci. 38: 319-323. (Corresponding author)


[2007 : SCI]

  • * 67. Baek, K.-H., Lee, E.-J. and Kim, Y.-S. (2007). Recurrent pregnancy loss: the key potential mechanisms. Trends Mol. Med. 13: 310-317. (Corresponding author)

  • * 66. Noh, S.M., Kim, W.-K., Kim, S.J., Kim, J.M., Baek, K.-H., and Oh, Y.-K. (2007). Enhanced cellular delivery and transfection efficiency of plasmid DNA using positively charged biocompatible colloidal gold nanoparticles. Biochim. Biophys. Acta 1770: 747-752. (Co-corresponding author)

  • * 65. Kim, Y.-K., Kim, Y.-S., Yoo, K.-J., Lee, H.-J., Lee, D.-R., Yeo, C.Y., and Baek, K.-H. (2007). The expression of Usp42 during embryogenesis and spermatogenesis in mouse. Mech. Dev. Gene Exp. Patterns 7: 143-148. (Corresponding author)


[2007 : non-SCI]

  • * 64. Kim, D.C., Noh, S.M., Park, K.T., Kim, Y.B., Baek, K.-H., and Oh, Y.-K. (2007). Transdermal delivery of porcine placenta extracts using linolenic acid-based emulsion formulations. J. Kor. Pharm. Sci. 37: 281-286. (Corresponding author)


[2006 : SCI]

  • * 63. Shin, J.-M., Yoo, K.-J., Kim, M.-S., Kim, D., and Baek, K.-H. (2006). Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability. BMC Genomics 7: 292. (Corresponding author)

  • 62. Kim, S.J., Lee, S.Y., Lee, C., Kim, I., An, H.J., Kim, J.Y., Baek, K.-H., Kim, E.J., Kim, J.M., Lee, J.B., Lee, J.W., Jung, W.W., Chun, T., and Oh, Y.K. (2006). Differential expression profiling of genes in a complete hydatidiform mole using cDNA microarray analysis. Gynecol Oncol. 103: 654-660.

  • * 61. Kim, Y.-S., Kim, Y.-K., Park, J.-M., Han, I.-S., Ajjappala, B.S., Kang, I., and Baek, K.-H. (2006). Disruption of protein-protein interaction for Mgl-1 oncoprotein. Oncol. Rep. 16: 795-800. (Corresponding author)

  • * 60. Kim, Y.-S., Kim, M.-S., Lee, S.-H., Choi, B.-C., Lim, J.-M., Cha, K.-Y., and Baek, K.-H. (2006). Proteomic analysis of recurrent spontaneous abortion: Identification of an inadequately expressed set of proteins in human follicular fluid. Proteomics 6: 3445-3454. (Corresponding author)

  • * 59. Cheon, K. W., and Baek, K.-H. (2006). HAUSP as a therapeutic target for hematopoietic tumors. Int. J. Oncol. 28: 1209-1215. (Corresponding author)

  • * 58. Lee, E.-J., Yoo, K.-J., Kim, S.-J., Lee, S.-H., Cha, K.Y., and Baek, K.-H. (2006). Single nucleotide polymorphism in exon 17 of the insulin receptor gene is not associated with polycystic ovary syndrome in a Korean population. Fertil. Steril. 86: 380-385 (Corresponding author)

  • * 57. Baek, K.-H. (2006). Cytokine-regulated protein degradation by the ubiquitination system. Curr. Protein Pept Sci. 7:171-177. (Corresponding author)

  • * 56. Lee, H.-J., Kim, M.-S., Shin, J.-M., Park, T.-J., Chung, H.-M., and Baek, K.-H. (2006). The expression patterns of deubiquitinating enzymes, USP22 and Usp22. Mech. Dev. Gene Exp. Patterns 6: 277-284. (Corresponding author)

  • * 55. Baek, K.-H., Lee, H.-J., Kim, M.-S., Kim, Y.-S., Seong, M., Lee, E.-J., and Lee, M.-Y. (2006). Molecular cloning of rHAUSP encoding a deubiquitinating enzyme in a rat testis. Oncol. Rep. 15: 173-177. (Corresponding author)

  • 54. Gu, Y.-M., Jin, Y.-H. Choi, J.-K., Baek, K.-H., Yeo, C.-Y., and Lee, K.-Y. (2006). Protein kinase A phosphorylates and regulates dimerization of 14-3-3 zeta. FEBS Lett. 580: 305-310.


[2006 : non-SCI]

  • 53. Park, J.-E., Jang, M.-H., Cho, S.-W., Kim, Y.-S., Won, H.-J., Cho, J.-H., Baek, K.-H., and Lee, S.-H. (2006). Mitochondrial DNA copy number in the patients of Korean polycystic ovary syndrome (PCOS). Kor. J. Fertil. Steril. 33: 245-251.


[2005 : SCI]

  • 52. Kang, I-C., Min, B., Ahn, E., Son, H., and Baek, K.-H. (2005). Expression of soluble recombinant integrin alpha V and beta 3 from SF21 cells with baculovirus expression vector for targeted screening of integrin antagonists. Kor. J. Genetics 27: 211-217.

  • * 51. Lee, H.-J., Kim, M.-S., Kim, Y.-K., Oh, Y.-K., and Baek, K.-H. (2005). HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated, polyneddylated, and dimerized. FEBS Lett. 579: 4867-4872. (Corresponding author)

  • * 50. Yoo, K.-J., Lee, H.-J., Lee, H., Lee, K.-Y., Lee, S.-H., Chung, H.-M., and Baek, K.-H. (2005). Expression and functional analyses of mHAUSP regulating apoptosis of cervical adenocarcinoma cells. Int. J. Oncol. 27: 97-104. (Corresponding author)

  • * 49. Kim, Y.-K., Kim, Y.-S., and Baek, K.-H. (2005). The WD-40 repeat motif of Lgl tumor suppressor proteins associated with salt tolerance and temperature sensitivity. Biochem. Biophys. Res. Commun. 331: 922-928. (Corresponding author)

  • * 48. Kim, M.-S., Kim, Y.-K., Kim, Y.-S., Seong, M. Choi, J.-K., and Baek, K.-H. (2005). Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated. Biochem. Biophys. Res. Commun. 330: 797- 804. (Corresponding author)

  • 47. Lee, J., Choi, B.-C., Cho, C., Hill, J. A., Baek, K.-H., and Kim, J.-W. (2005). Trophoblast apoptosis is increased in women with evidence of Th-1 immunity. Fertil. Steril. 83: 1047-1049.


[2005 : non-SCI]

  • * 46. Lee, M.-Y., and Baek, K.-H. (2005). Regulation of insulin signaling through protein degradation. Kor. J. Endocrinol. 20: 434-440. (Corresponding author)

  • * 45. Seong, M., Kim, M.-S., Kim, Y.-S. Lee, S.-H., Lee, H.-J., Cha, K.-Y., and Baek, K.-H. (2005). HIDE, a testis specific deubiquitinating enzyme, interacts with HSP90. Kor. J. Fertil. Steril. 32: 231-242. (Corresponding author)

  • * 44. Lee, E.-J., Yoo, K.-J., Kim, S.J., Lee, S.H., Choi, D.H., Cha, K.Y., Choi, D.S., and Baek, K.-H. (2005). Relationship between the C/T single nucleotide polymorphism in exon 17 of the insulin receptor gene and polycystic ovary syndrome. J. Biol. Sci. 5: 832-836. (Corresponding author)


[2004 : SCI]

  • * 43. Kim, Y.-K., Kim, Y.-S., Chung, H.-M., and Baek, K.-H. (2004). Complementation of temperature tolerance by rat Rgl-1 recessive oncogene in the absence of Saccharomyces cerevisiae Sop genes. Oncol. Rep. 12: 1105-1108. (Corresponding author)

  • * 42. Baek, K.-H., Kim, Y.-S., Lee, H.-J., and Kang, I. (2004). The essential regions for deubiquitinating enzyme activity and enhancer function for DUB-2A expressed in T-lymphocytes. Arch. Biochem. Biophys. 430: 191-197. (Corresponding author)

  • * 41. Kim, M.-S., Yoo, K.-J., Kang, I., Chung, H. M., and Baek, K.-H. (2004). A novel cysteine protease HeLa DUB-1 responsible for cleaving the ubiquitin in human ovarian cancer cells. Int. J. Oncol. 25: 373-379. (Corresponding author)

  • * 40. Kim, K.-S., Kim, M.-S., Kim, S.-K., and Baek, K.-H. (2004). Murine Asb-17 expression during mouse testis development and spermatogenesis. Zygote 12: 151-156. (Corresponding author)

  • * 39. Baek, K.-H. (2004). Structural and functional conservation of the lgl recessive oncogenes. Int. J. Oncol. 24: 1257-1262. (Corresponding author)

  • * 38. Baek, K.-H. (2004). Aberrant gene expression associated with recurrent pregnancy loss. Mol. Hum. Reprod. 10: 291-297. (Corresponding author)

  • 37. Burrows, J. F., McGrattan, M. J., Rascle, A., Humbert, M., Baek, K.-H., and Johnston, J. A. (2004). DUB-3, a cytokine inducible deubiquitinating enzyme that blocks proliferation. J. Biol. Chem. 279: 13993-14000.

  • 36. Jeon, S. Y., Baek, K.-H., Kim, Y.-S., Kwon, H. S., Ko, S. H., Song, K. -H., Yoo, S. J., Son, H. S., Cha, B. Y., Lee, K.W., Son, H. Y., Kang, S. K., and Yoon, K. H. (2004). Differentially up-regulated genes in proliferating porcine neonatal pancreas cells caused by epidermal growth factor. J. Cell. Biochem. 91: 354-364.

  • * 35. Lim, S.-K., Shin, J.-M., Kim, Y.-S., and Baek, K.-H. (2004). Identification and characterization of murine mHAUSP encoding a deubiquitinating enzyme that regulates the status of p53 ubiquitination. Int. J. Oncol. 24: 357-364. (Corresponding author)

  • * 34. Baek, K.-H., Kim, M.-S., Kim, Y.-S., Shin, J.-M., and Choi, H.-K. (2004). DUB-1A, a novel subfamily member of deubiquitinating enzyme, is polyubiquitinated and cytokine-inducible in B lymphocytes. J. Biol. Chem. 279: 2368-2376. (Corresponding author)


[2004 : non-SCI]

  • 33. Hwang, K. R., Choi, Y. M., Choi, D., Baek, K.-H., Bae K. B., Son, Y. S., Ku, S. Y., Jee, B. C., Suh, C. S., Kim, S. H., Ki, J. G., and Moon, S. Y. (2004). Effect of metformin treatment and insulin resistance in patients with polycystic ovary syndrome. Kor. J. Obs. Gyn. 47: 1949-1953.


[2003 : SCI]

  • * 32. Kim, Y.-S., Song, J., Kim, Y.-K., Kim, I.-O., Kang, I., and Baek, K.-H. (2003). Functional and expression analyses of mgl-1, a mouse orthologue of lethal giant larvae recessive oncogene. Int. J. Oncol. 23: 1515-1519. (Corresponding author)

  • 31. Chung, K.-H., Kim, S.-H., Han, K.-Y., Sohn, Y.-D., Chang, S.-I., Baek, K.-H., Kim, D.-S., and Kang, l. (2003). Inhibitory effect of salmosin, a Korean snake venom-derived disintegrin, on integrin av-mediated proliferation of SK-Mel-2 human melanoma cells. J. Pharm. Pharmacol. 55: 1577-1582.

  • * 30. Choi, H.-K., Choi, B. C., Lee, S.-H., Kim, J. W. Cha, K. Y., and Baek, K.-H. (2003). Expression of angiogenesis- and apoptosis-related genes in chorionic villi derived from recurrent pregnancy loss patients. Mol. Reprod. Dev. 66: 24-31. (Corresponding author)

  • * 29. Kim, Y.-S., Chung, H. M., and Baek, K.-H. (2003). WD-40 repeat containing rat lethal giant larvae recessive oncogene, but not tomosyn, restores the salt sensitivity in Saccharomyces cerevisiae. Int. J. Oncol. 23: 229-233. (Corresponding author)

  • * 28. Baek, K.-H. (2003). Conjugation and deconjugation of ubiquitin regulating the destiny of proteins. Exp. Mol. Med. 35: 1-7. (Corresponding author)


[2003 : non-SCI]

  • 27. Lee, K.-W., Jeong, Y.-M., Lee, S.-H., Yoon, T. K., Kwak, I. P., Yoon, S. W., Choi, J. S., Kim, K. H., Han, J. S., Kim, S. D., Kim, N. K., Cha, K. Y., Baek, K.-H., and Lee, S. (2003). The study of 5,10-methylenetetrahydrofolate reductase variation (MTHFR C677T) in fertile females with polycystic ovarian syndrome (PCOS) in Korea. Kor. J. Fertil. Steril. 30: 217-222.

  • * 26. Shin, J.-M., Kim, J.-W., Choi, B., Lee, S.-H., and Baek, K.-H. (2003). Expression of immunosuppression-related genes in fetal chorionic villi derived from recurrent spontaneous abortion patients. Kor. J. Fertil. Steril. 30: 233-240. (Corresponding author)


[2002 : SCI]

  • * 25. Lim, S.-K., Kim, M.-S., Lee, S.-H., and Baek, K.-H. (2002). Polymorphism of CYP17 and CYP11a for polycystic ovary syndrome in a korean population. Kor. J. Genetics 24: 343-348. (Corresponding author)

  • * 24. Baek, K.-H., Choi, B. C., Lee, J.-H., Choi, H.-K. Lee, S.-H., Kim, J.-W., Hill, J. A., Chung, H.-M., Ko, J. J., and Cha, K. Y. (2002). Comparison of gene expression at the feto-maternal interface between normal and recurrent pregnancy loss patients. Reprod. Fertil. Dev. 14: 235-240. (Corresponding author)

  • * 23. Baek, K.-H. (2002). Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines. Am. J. Hematol. 71: 340-345. (Corresponding author)

  • * 22. Baek, K.-H., Park, K.-H., Kim, Y.-S., Kim, M.-S., and Choi, H.-K. (2002). Molecular cloning and complete cDNA sequence of UBH1 in mouse testis. DNA Seq. 13: 145-148. (Corresponding author)

  • * 21. Kim, Y.-S., Baek , K.-H., Lee, K. Y., Chung, H.-M., Lee, K.-A., Ko, J.J. and Cha, K. Y. (2002). The rgl-1 is a legitimate homologue of lethal (2) giant larvae recessive oncogene in rat. Int. J. Oncol. 20: 1219-1225. (Corresponding author)

  • * 20. Baek, K.-H., Kim., Y.-S., Chung, H. -M., Ko, J. J. and Cha, K. Y. (2002). Conservation of the lethal giant larvae tumor suppressor gene in Bos taurus coreanae. Kor. J. Genetics 24: 127-132. (Corresponding author)

  • * 19. Baek, K.-H., Kim., Y.-S., Jung, S., Lee, K.-Y., Choi, H.-K., and Kim, K.-S. (2002). Molecular cloning and characterization of bovine bgl-1, a novel family member of WD-40 repeat containing lethal giant larval tumor suppressor genes. Int. J. Oncol. 20: 739-744. (Corresponding author)


[2001 : SCI]

  • 18. Baek, K.-H., Mondoux, M. A. Jaster, R., Fire-Levin, E., and D'Andrea, A. D. (2001). DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes. Blood 98: 636-642.

  • * 17. Lee, J.-H., Kim, Y.-S., Kim, M., and Baek, K.-H. (2001). Critical regions for deubiquitinating activity of DUB-2 expressed in T lymphocytes. Am. J. Hematol. 67: 270-272. (Corresponding author)

  • * 16. Baek, K.-H. (2001). Heartless, a fibroblast growth factor receptor, is required for embryonic muscle development in Drosophila. Kor. J. Genetics, 23: 151-156. (Corresponding author)

  • * 15. Lee, J.-H., Kim, Y.-S., Kang, W.-P., Chung, H.-M., and Baek, K.-H. (2001). Temporal enzymatic activity of lymphocyte-specific deubiquitinating enzymes. Kor. J. Genetics 23: 3-6. (Corresponding author)


[2001 : non-SCI]

  • * 14. Choi, B. C., Kim, J. W., Lee, J., Yoo, K. J., Byun, H. K., Hwang, C. S., Moon, I. K., Kim, S. N., and Baek, K.-H. (2001). The effect of exocelomic fluid in the first trimester pregnancy on trophoblast cell proliferation in vitro. Kor. J. Obs. Gyn. 44: 1678-1684. (Corresponding author)


[2000 : SCI]

  • * 13. Baek, K.-H., Kim M. K., Lee, K. Y., and Cha, K. Y. (2000). Raf serine/threonine kinase is required for early embryogenesis in Drosophila. Kor. J. Genetics 22: 63-70. (Corresponding author)


[1999 : SCI]

  • * 12. Baek, K.-H., and Lee, K. Y. (1999). Signal transduction pathway for anterior-posterior development in Drosophila. J. Biomed. Sci. 6: 314-319. (Corresponding author)

  • 11. Jaster, R., Baek, K.-H., and D'Andrea. (1999). Analysis of cis-acting sequences and trans-acting factors regulating the interleukin-3 response element of the murine DUB-1 gene. Biochim. Biophys. Acta 1446: 308-316.

  • * 10. Baek, K.-H. (1999). The application of temperature-sensitive mutations in Drosophila. Arch. Pharm. Res. 22: 229-231. (Corresponding author)

  • * 9. Baek, K.-H. (1999). The first oncogene in Drosophila melanogaster. Mut. Res. 436: 131-136. (Corresponding author)


[1998 : SCI]

  • 8. Michelson, A. M., Gisselbrecht, S., Zhou, Y., Baek, K.-H., and Buff, E. M. (1998). Dual functions of the heartless fibroblast growth factor receptor in development of the Drosophila embryonic development. Dev. Genetics 22: 212-229.


[1997 : SCI]

  • * 7. Baek, K.-H., and Hanratty, W. P. (1997). The l(2)gl, a recessive oncogene, is required during embryonic and post-embryonic development in Drosophila. Cancer Lett. 111: 233-238. (Corresponding author)

  • 6. Radke, K., Baek, K.-H., and Ambrosio, L. (1997). Characterization of maternal and zygotic D-raf proteins: dominant negative effects on Torso signal transduction. Genetics 145: 163-171.


[1996 : SCI]

  • 5. Johansen, K. M., Johansen, J., Baek, K.-H., and Yin, Y. (1996). Remodeling of nuclear architecture during the cell cycle in Drosophila embryos. J. Cell. Biochem. 63: 268-279.

  • * 4. Baek, K.-H., and Hanratty, W. P. (1996). The characterization of temperature-sensitive lethal (2) giant larvae alleles in Drosophila melanogaster. Drosophila Infor. Serv. 77: 90-92. (Corresponding author)

  • 3. Baek, K.-H., Fabian, J., Sprenger, F., Morrison, D., and Ambrosio, L. (1996). The activity of D-raf in Torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting. Dev. Biol. 175: 191-204.


[1994 : SCI]

  • * 2. Baek, K.-H., and Ambrosio, L. (1994). An efficient method for microinjection of mRNA into Drosophila embryos. BioTechniques 17: 1024-1026. (Corresponding author)

  • 1. Hiriyanna, K. T., Baedke, D., Baek, K.-H., Forney, B. A., Kordiyak, G., and Ingebritsen, T. S. (1994). Thiophosphorylated substrate analogs are potent active site-directed inhibitors of protein-tyrosine phosphatases. Anal. Biochem. 223: 51-58.

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